Scientific Publications

Point-of-Care Fluorescence Biosensing System for Rapid Multi-Allergen Screening. Demuru, Silvia, Hui Chai-Gao, Yevhen Shynkarenko, Nicola Hermann, Patricia-Daiana Boia, Peter Cristofolini, Bradley Petkus, Silvia Generelli, Samantha Paoletti, Stefano Cattaneo and Loïc Burr. 2024. Sensors, Volume 24, issue 11: 3280. https://doi.org/10.3390/s24113280 

Maternal gluten, cereal, and dietary fiber intake during pregnancy and lactation and the risk of islet autoimmunity and type 1 diabetes in the child. Leena Hakola, Nicolai A Lund-Blix, Hanna-Mari Takkinen, Heli Tapanainen, Sari Niinistö, Tuuli E Korhonen, Lars C Stene, Heikki Hyöty, Jorma Toppari, Jorma Ilonen, Mikael Knip, Riitta Veijola, Suvi M Virtanen & HEDIMED Investigator group. Clinical nutrition ESPEN. Volume 62, pages 22-27. August 2024, available online May 2024. https://doi.org/10.1016/j.clnesp.2024.05.001 

No association between long-chain n-3 fatty acid intake during pregnancy and risk of type 1 diabetes in offspring in two large Scandinavian pregnancy cohorts. Nicolai
Lund-Blix, Anne Bjerregaard, German Tapia, Ketil Størdal, Anne Lise Brantsæter, Marin Strøm, Thorhallur I. Halldorsson, Charlotta Granstrøm, Jannet Svensson, Geir Joner, Torild Skrivarhaug, Pål R. Njølstad, Sjurdur F. Olsen, Lars C. Stene. Diabetologia. March 2024.  https://link.springer.com/article/10.1007/s00125-024-06125-4

Effects of Lactiplantibacillus plantarum and Lacticaseibacillus paracasei supplementation on the single-cell fecal parasitome in children with celiac disease autoimmunity: a randomized, double-blind placebo-controlled clinical
trial. Jacub Hurych, Elin Oscarsson, Åsa Håkanson, Kateřina Jirků-Pomajbíková, Milan Jirků, Carin Andrén Aronson, Ondřej Cinek, Daniel Agardh & the HEDIMED Investigator Group.  Parasites Vectors. Volume 16, Article number: 411. November 2023. https://doi.org/10.1186/s13071-023-06027-1

The edible plant microbiome: evidence for the occurrence of fruit and vegetable bacteria in the human gut. Wisnu Adi Wicaksono, Tomislav Cernava, Birgit Wassermann, Ahmed Abdelfattah, Maria J. Soto-Giron, Gerardo V. Toledo, Suvi M. Virtanen, Mikael Knip, Heikki Hyöty & Gabriele Berg. Gut Microbes. Volume 15, Issue 2. September 2023.  https://doi.org/10.1080/19490976.2023.2258565

Atopic sensitization in childhood depends on the type of green area around the home in infancy. Tiia Voor, Meelis Pärtel, Aleksandr Peet, Liisa Saare, Heikki Hyöty, Mikael Knip, John Davison, Martin Zobel, Vallo Tillmann. Clinical & Experimental Allergy.  Volume 53, Issue 8, August 2023. Doi:https://doi.org/10.1111/cea.14317

Exposures to perfluoroalkyl substances and asthma phenotypes in childhood: an investigation of the COPSAC2010 cohort. Astrid Sevelsted, Casper-Emil Pedersen, Gözde Gürdeniz, Morten Rasmussen, Jörg Schullehner, Kalliroi Sdougkou, Jonathan W. Martin, Jessica Lasky-Su, Andreanne Morin, Carole Ober, Ann-Marie Schoos, Jakob Stokholm, Klaus Bønnelykke, Bo Chawes & Hans Bisgaard. eBioMedicine, part of the Lancet Discovery Science. Volume 94, August 2023, 104699 https://doi.org/10.1016/j.ebiom.2023.104699

Effects of Lactiplantibacillus plantarum and Lacticaseibacillus paracasei supplementation on the faecal metabolome in children with coeliac disease autoimmunity: a randomised, double-blinded placebo-controlled clinical trial. Eliska Jenickova, Carin Andrén Aronsson, Anna Mascellani Bergo, Ondrej Cinek, Jaroslav Havlik, Daniel Agardh. Frontiers in Nutrition. Volume 10 – 2023 https://doi.org/10.3389/fnut.2023.1183963

Skin, gut, and sand metagenomic data on placebo-controlled sandbox biodiversity intervention study. Marja I. Roslund, Anirudra Parajuli, Nan Hui, Riikka Puhakka, Mira Grönroos, Laura Soininen, Noora Nurminen, Sami Oikarinen, Ondřej Cinek, Lenka
Kramná, Anna-Mari Schroderus, Olli H. Laitinen, Tuure Kinnunen, Heikki Hyöty, Aki Sinkkonen. Data in Brief , Volume 47, February 2023, 109003, ISSN 2352-3409, https://doi.org/10.1016/j.dib.2023.109003 (*Data related to the study of Roslund et al. 2022)

Modulation of the food microbiome by apple fruit processing. Wisnu Adi Wicaksono, Aisa Buko, Peter Kusstatscher, Aki Sinkkonen, Olli H. Laitinen, Suvi M. Virtanen, Heikki Hyöty, Tomislav Cernava, Gabriele Berg. Food Microbiology, Volume 108, December 2022, 104103. doi:https://doi.org/10.1016/j.fm.2022.104103

Impact of Cultivation and Origin on the Fruit Microbiome of Apples and Blueberries and Implications for the Exposome. Wisnu A. Wicaksono, Aisa Buko, Peter Kusstatscher, Tomislav Cernava, Aki Sinkkonen, Olli H. Laitinen, Suvi M. Virtanen,  Heikki Hyöty &
Gabriele Berg. December 2022. Microbial ecology, 10.1007/s00248-022-02157-8. Advance online publication. https://doi.org/10.1007/s00248-022-02157-8

A Placebo-controlled double-blinded test of the biodiversity hypothesis
of immune-mediated diseases: Environmental microbial diversity elicits
changes in cytokines and increase in T regulatory cells in young children. Marja I. Roslund, Anirudra Parajuli, Nan Hui, Riikka Puhakka, Mira Grönroos, Laura Soininen, Noora Nurminen, Sami Oikarinen, Ondřej Cinek, Lenka Kramná, Anna-Mari Schroderus, Olli H. Laitinen, Tuure Kinnunen, Heikki Hyöty, Aki Sinkkonen, ADELE research group. Ecotoxicol Environ, Saf: 2022 August 2;242:113900. doi: 10.1016/j.ecoenv.2022.113900 (*See also Data in Brief article of Roslund et al. 2023)

Land Cover of Early-Life Environment Modulates the Risk of Type 1 Diabetes. Noora
Nurminen, Damiano Cerrone, Jussi Lehtonen, Anirudra Parajuli, Marja Roslund, Maria Lönnrot, Jorma Ilonen, Jorma Toppari, Riitta Veijola, Mikael Knip, Juho Rajaniemi, Olli H. Laitinen, Aki Sinkkonen, Heikki Hyöty. Diabetes Care July 2021, 44 (7) 1506-1514; DOI: 10.2337/dc20-1719 https://care.diabetesjournals.org/content/44/7/1506

Parechovirus Infection in Early Childhood and Association With Subsequent Celiac Disease. Tapia, German; Chudá, Kateřina; Kahrs, Christian R.; Stene, Lars C.; Kramna,
Lenka; Mårild, Karl; Rasmussen, Trond; Rønningen, Kjersti S.; Cinek, Ondřej; Størdal, Ketil. The American Journal of Gastroenterology: April 2021 – Volume 116 – Issue 4 – p 788-795 doi:10.14309/ajg.0000000000001003 https://journals.lww.com/ajg/Fulltext/2021/04000

Exposomic determinants of immune-mediated diseases – a special focus on type 1 diabetes, celiac disease, asthma and allergies; The HEDIMED project approach. Jutta E. Laiho, Olli H. Laitinen, Johannes Malkamäki, Leena Puustinen, Aki Sinkkonen, Juha Pärkkä, Heikki Hyöty and the HEDIMED Investigator group. Environmental Epidemiology, June 2022 – Volume 6 – Issue 3 – p e212, doi: 10.1097/EE9.0000000000000212 https://journals.lww.com/environepidem/Fulltext/2022/06000/Exposomic_determinants_of_immune_mediated.6.aspx