Scientific Publications

Exposomic determinants of immune-mediated diseases – a special focus on type 1 diabetes, celiac disease, asthma and allergies; The HEDIMED project approach

Jutta E. Laiho, Olli H. Laitinen, Johannes Malkamäki, Leena Puustinen, Aki Sinkkonen, Juha Pärkkä, Heikki Hyöty and the HEDIMED Investigator group. Environmental Epidemiology, June 2022 – Volume 6 – Issue 3 – p e212, doi: 10.1097/EE9.000000000000021 https://journals.lww.com/environepidem/Fulltext/2022/06000/Exposomic_determinants_of_immune_mediated.6.aspx 

A Placebo-controlled double-blinded test of the biodiversity hypothesis of immune-mediated diseases: Environmental microbial diversity elicits changes in cytokines and increase in T regulatory cells in young children

Marja I. Roslund, Anirudra Parajuli, Nan Hui, Riikka Puhakka, Mira Grönroos, Laura Soininen, Noora Nurminen, Sami Oikarinen, Ondřej Cinek, Lenka Kramná, Anna-Mari Schroderus, Olli H. Laitinen, Tuure Kinnunen, Heikki Hyöty, Aki Sinkkonen, ADELE research group. Ecotoxicol Environ Saf: 2022 Aug 2;242:113900. doi: 10.1016/j.ecoenv.2022.113900 https://pubmed.ncbi.nlm.nih.gov/35930838/ 

Modulation of the food microbiome by apple fruit processing

Wisnu Adi Wicaksono, Aisa Buko, Peter Kusstatscher, Aki Sinkkonen, Olli H. Laitinen, Suvi M. Virtanen, Heikki Hyöty, Tomislav Cernava, Gabriele Berg. Food Microbiology, Volume 108, December 2022, 104103. doi: 10.1016/j.fm.2022.104103 https://www.sciencedirect.com/science/article/pii/S0740002022001277?utm_campaign=STMJ_AUTH_SERV_PUBLISHED&utm_medium=email&utm_acid=76936073&SIS_ID=&dgcid=STMJ_AUTH_SERV_PUBLISHED&CMX_ID=&utm_in=DM284894&utm_source=AC_

Land Cover of Early-Life Environment Modulates the Risk of Type 1 Diabetes

Noora Nurminen, Damiano Cerrone, Jussi Lehtonen, Anirudra Parajuli, Marja Roslund, Maria Lönnrot, Jorma Ilonen, Jorma Toppari, Riitta Veijola, Mikael Knip, Juho Rajaniemi, Olli H. Laitinen, Aki Sinkkonen, Heikki Hyöty
Diabetes Care Jul 2021, 44 (7) 1506-1514; DOI: 10.2337/dc20-1719 https://care.diabetesjournals.org/content/44/7/1506

Parechovirus Infection in Early Childhood and Association With Subsequent Celiac Disease

Tapia, German; Chudá, Kateřina; Kahrs, Christian R.; Stene, Lars C.; Kramna, Lenka; Mårild, Karl; Rasmussen, Trond; Rønningen, Kjersti S.; Cinek, Ondřej; Størdal, Ketil. The American Journal of Gastroenterology: April 2021 – Volume 116 – Issue 4 – p 788-795 doi:1 10.14309/ajg.0000000000001003 https://journals.lww.com/ajg/Fulltext/2021/04000