Simulation model of natural history of T1D with primary and / or secondary prevention that shows how disease incidence can be reduced significantly if currently assessed interventions prove efficacious enterovirus vaccine (teplizumab).
Celiac disease pathogenesis, in addition to immune cell component, encompasses pathogenic events also in the duodenal epithelium. In celiac disease patients, exposure to dietary gluten induces drastic changes in epithelial differentiation and elicit cellular response to inflammatory cytokines. The autoantigen in celiac disease, transglutaminase 2 (TG2) enzyme, has been also suggested to play its pathogenic…
The Array-in-well (AiW) platform is a high-throughput array-based multiplex assay platform that offers a sample-saving alternative to replacing or complementing ELISA in serological analyses. The AiW platform consists of dot arrays printed at the bottom of microtiter plate wells. Each well can contain nearly a hundred dots of different bio-affinity reagents, such as antibodies, antigens,…
The geocoder converts addresses to coordinates and produces a csv file with coordinates in the output directory. The method is based on the geopy Python package, see https://geopy.readthedocs.io/en/stable/ for detailed information. Requirements Ubuntu operating system + Python3 Usage python3 geocoder.py [csv filename with addresses in input directory] Example: python3 geocoder.py sample_input.csv The input csv file should…
This tool will show relations between exposome and risk factors and IMDs based on scientific evidence with expert comment.
A 500 MHz spectrometer dedicated to metabolomics of biological samples, with standard protocols for faecal, urine, and plasma analysis, is a powerful tool capable of monitoring the concentrations of 30-60 small molecular metabolites in each sample. It is suitable for robust screening of biological samples in clinical studies or epidemiological cohorts. This spectrometer allows for…
The device is a tool for measurements of specific IgE-mediated fluorescence responses in serum samples, indicating the likelihood of an allergic response to different allergens deposited in a microfluidic device. Features: Read more about the tool here: https://www.hedimed.eu/novel-technologies-used-in-hedimed-portable-allergy-testing