A set of interlocked functions used to accelerate analysis of Olink proteomics data including endpoints. The idea is to have a standard syntax to enable the same types of analyses with multiple cohorts, datasets, and endpoints.
The functions are used in R, using the RStudio interface on the HEDIMED analysis platform, but can be exported to other R environments
A 500 MHz spectrometer dedicated to metabolomics of biological samples, with standard protocols for faecal, urine, and plasma analysis, is a powerful tool capable of monitoring the concentrations of 30-60 small molecular metabolites in each sample. It is suitable for robust screening of biological samples in clinical studies or epidemiological cohorts. This spectrometer allows for…
A comparison and assessment of EU and national allergy guidelines, including recommendations, based on up-to-date scientific expertise in the HEDIMED consortium.
Celiac disease pathogenesis, in addition to immune cell component, encompasses pathogenic events also in the duodenal epithelium. In celiac disease patients, exposure to dietary gluten induces drastic changes in epithelial differentiation and elicit cellular response to inflammatory cytokines. The autoantigen in celiac disease, transglutaminase 2 (TG2) enzyme, has been also suggested to play its pathogenic…
Simulation model of natural history of T1D with primary and / or secondary prevention that shows how disease incidence can be reduced significantly if currently assessed interventions prove efficacious enterovirus vaccine (teplizumab).
Terramonitor Geosampler calculates the zonal statistics (mean, maximum, minimum etc.) from a raster file containing geographical information, around coordinate points defined in the input file with a given radius in meters. Produces a csv file in the output directory with zonal statistics added to the points. The method is based on the QGIS Zonal Statistics…
The device is a tool for measurements of specific IgE-mediated fluorescence responses in serum samples, indicating the likelihood of an allergic response to different allergens deposited in a microfluidic device. Features: Read more about the tool here: https://www.hedimed.eu/novel-technologies-used-in-hedimed-portable-allergy-testing